HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzamide → 2-(3-fluorophenyl)-7-methoxy-8-methyl-1H-quinazolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzamide | HCID 2331 | — |
| Reactant | 3-Fluorobenzoyl chloride | HCID 74376 | — |
| Reactant | 2-Amino-4-methoxy-3-methylbenzamide | HCID 59165435 | — |
| Product | 2-(3-fluorophenyl)-7-methoxy-8-methyl-1H-quinazolin-4-one | HCID 178487730 | 73% |
Reaction Steps
The general procedure described in Example 10 was followed using 2-amino-4-methoxy-3-methyl benzamide as benzamide derivative [A] and 3-fluoro-benzoyl chloride as acid chloride [B], which gave the title compound (2.1 g, 73%), [M+H]=271.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754105B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-8e2d63587aea424ea929e58fb10092f9 |
| Source note | uspto-grants-2014_06 |