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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 406427Generated: October 30, 2026

Hydrazine hydrate (1:1) → HCID 58118987, compound

https://huagongshe.com/reaction/406427

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
ReactantHCID 12671443HCID 12671443—
SolventEthanolHCID 702—
ProductHCID 58118987HCID 58118987—

Reaction Steps

To a solution of 2-chloro-5-(4-phenoxyphenyl)pyrazine in 2 mL of ethanol was added hydrazine monohydrate (2 mL). The reaction mixture was heated at 110 C for 2 hours and evaporated in vacuo. The residue was dissolved in dicholomethane, washed with water, dried over Na2SO4, and evaporated in vacuo to afford 2-hydrazinyl-5-(4-phenoxyphenyl)pyrazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754103B2
Source datasetuspto-grants-2014_06
ORD IDord-cec20bbb48ae4528a954b8b7471e5254
Source noteuspto-grants-2014_06