4-Hydroxypyrrolidine → HCID 59764665, compound

HRID 406471Notes

Reaction equation

HRID 406471 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][C:14]=1[Cl:15])[C:5]([NH:7][CH2:8][C:9]([OH:11])=O)=[O:6].[NH:16]1[CH2:20][CH2:19][CH:18]([OH:21])[CH2:17]1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][C:14]=1[Cl:15])[C:5]([NH:7][CH2:8][C:9]([N:16]1[CH2:20][CH2:19][CH:18]([OH:21])[CH2:17]1)=[O:11])=[O:6]

Participants

3

Reactant 2

HCID 982104-HydroxypyrrolidineHCID 260363N-(3,4-Dichlorobenzoyl)glycine

Product 1

HCID 59764665HCID 59764665, compound

Procedure

The titled compound was prepared from (3,4-dichloro-benzoylamino)-acetic acid (preparation #14) and pyrrolidin-3-ol according to the general procedure G. m/z: (M+H)+ 317.

Sources & evidence

ORD record
ord-c94953f18a484083b9b8053dd5eadd9c
Source dataset
uspto-grants-2014_06
Patent number
US08754107B2

Reaction notes

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