HCID 68901881, compound → HCID 59764630, compound

HRID 406499Notes

Reaction equation

HRID 406499 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[C:15]3[NH:14][C:13](=[O:16])[NH:12][C:11]=3[CH:10]=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.[Cl:17][C:18]1[CH:19]=[C:20]([CH:33]=[CH:34][C:35]=1[Cl:36])[C:21]([NH:23][CH2:24][C:25](=[O:32])[N:26]1[CH2:30][CH2:29][C:28](=O)[CH2:27]1)=[O:22]>>[Cl:17][C:18]1[CH:19]=[C:20]([CH:33]=[CH:34][C:35]=1[Cl:36])[C:21]([NH:23][CH2:24][C:25](=[O:32])[N:26]1[CH2:27][CH2:28][CH:29]([N:1]2[CH2:2][CH2:3][CH:4]([C:7]3[C:15]4[NH:14][C:13](=[O:16])[NH:12][C:11]=4[CH:10]=[CH:9][CH:8]=3)[CH2:5][CH2:6]2)[CH2:30]1)=[O:22]

Participants

3

Reactant 2

HCID 68901881HCID 68901881, compoundHCID 68975830HCID 68975830, compound

Product 1

HCID 59764630HCID 59764630, compound

Procedure

The title compound was prepared from 4-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one and 3,4-dichloro-N-(2-oxo-2-(3-oxopyrrolidin-1-yl)ethyl)benzamide using general procedure E. HPLC (Table 1, Method b) Rt 1.73 min; m/z: (M+H)+ 516.

Sources & evidence

ORD record
ord-f096490db7e84c01be6e1c2b5470f3e2
Source dataset
uspto-grants-2014_06
Patent number
US08754107B2

Reaction notes

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