Benzylamine → HCID 10403869, compound

HRID 406504Notes

Reaction equation

HRID 406504 reaction equation
[CH3:1][C@@:2]12[CH:9]=[CH:8][C:7](=[O:10])[N:6]1[C@@H:5]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH2:4][O:3]2.[CH2:17]([NH2:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([NH:24][C@H:9]1[C@@:2]2([CH3:1])[O:3][CH2:4][C@H:5]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)[N:6]2[C:7](=[O:10])[CH2:8]1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 7157228(3S,7aR)-7a-Methyl-3-phenyl-2,3-dihydropyrrolo[2,1-b][1,3]oxazol-5(7aH)-one

Product 1

HCID 10403869HCID 10403869, compound

Procedure

(3S,7R,7aR)-7-(Benzylamino)-7a-methyl-3-phenyltetrahydropyrrolo[2,1-b]oxazol-5(6H)-one was synthesized from (3S,7aR)-7a-methyl-3-phenyl-2,3-dihydropyrrolo[2,1-b]oxazol-5(7aH)-one and benzyl amine using general procedure Y. RP-HPLC (Table 1, Method a) Rt 1.73; m/z: (M+H)+ 323.

Sources & evidence

ORD record
ord-1b0be56142b44944b9c244cb1eb42178
Source dataset
uspto-grants-2014_06
Patent number
US08754107B2

Reaction notes

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