3-Chloropropiophenone → HCID 13867052, compound

HRID 406712Notes

Reaction equation

[Cl:1][CH2:2][CH2:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5].[CH3:12][Mg]Br>>[Cl:1][CH2:2][CH2:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)([OH:5])[CH3:12]

Participants

Reactant 2

HCID 702953-Chloropropiophenone

HCID 178418573HCID 178418573, compound

Product 1

HCID 13867052HCID 13867052, compound

Procedure

4-chloro-2-phenylbutan-2-ol was prepared from 3-chloro-1-phenylpropan-1-one and methylmagnesium bromide following a procedure analogous to that described in Preparation 1 Method 1 Step 2.

Workup

customthat described in Preparation 1 Method 1 Step 2

Sources & evidence

ORD record: ord-2e083e82ef7d409baf6b8f5b29972599
Source dataset: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08754076B2

Reaction notes

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