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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 406720Generated: October 30, 2026

2,2,2-Trifluoroethyl trifluoromethanesulfonate → 5-Bromo-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one

https://huagongshe.com/reaction/406720

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,2-Trifluoroethyl trifluoromethanesulfonateHCID 80366—
Reactant5-Bromo-2-hydroxypyridineHCID 599528—
Product5-Bromo-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-oneHCID 53408099—

Reaction Steps

5-bromo-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one was prepared from 5-bromopyridin-2(1H)-one and 2,2,2-trifluoroethyl trifluoromethanesulfonate following a procedure analogous to that described in Example 59 Step 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754076B2
Source datasetuspto-grants-2014_06
ORD IDord-65e30dbe762f4384bf888307e5a0470f
Source noteuspto-grants-2014_06