Furfurylamine → N-(Tetrahydrofuran-2-ylmethyl)-4-{1-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]-1H-benzimidazol-5-yl}benzamide

Participants

Role	Name	HCID	Charge
Reactant	Furfurylamine	HCID 3438	—
Reactant	4-{1-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]-1H-benzimidazol-5-yl}benzoic acid	HCID 67979982	—
Product	N-(Tetrahydrofuran-2-ylmethyl)-4-{1-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]-1H-benzimidazol-5-yl}benzamide	HCID 57386417	—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 7 starting from 4-{1-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)-phenyl]-1H-benzimidazol-5-yl}benzoic acid and 2-furanmethanamine, tetrahydro- (Aldrich, Cat. No. 131911). LCMS (M+H)+: m/z=538.3.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08754114B2
Source dataset	uspto-grants-2014_06
ORD ID	ord-b18a6f208b64420d84eeac5ac70c0a6f
Source note	uspto-grants-2014_06