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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 406996Generated: October 30, 2026

3-Isocyanatopyridine → HCID 57387174, compound

https://huagongshe.com/reaction/406996

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-IsocyanatopyridineHCID 2760493—
ReactantN-{3-[5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-1H-benzimidazol-1-yl]phenyl}-N'-(2,2,2-trifluoroethyl)urea HCl saltHCID 67980207—
ProductHCID 57387174HCID 57387174—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 24 starting from N-{3-[5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-1H-benzimidazol-1-yl]phenyl}-N′-(2,2,2-trifluoroethyl)urea HCl salt (prepared from the procedure for Example 21, step 4) and 3-isocyanatopyridine (Oakwood, Cat. No. 022077), LCMS (M+H)+: m/z=604.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754114B2
Source datasetuspto-grants-2014_06
ORD IDord-86f3d9c93b494a4ba1093665cc26abe6
Source noteuspto-grants-2014_06