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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 407000Generated: October 30, 2026

(+-)-Tetrahydro-2-furoic acid → HCID 57387427, compound

https://huagongshe.com/reaction/407000

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-Tetrahydro-2-furoic acidHCID 86079—
ReactantN-{3-[5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-1H-benzimidazol-1-yl]phenyl}-N'-(2,2,2-trifluoroethyl)urea HCl saltHCID 67980207—
ProductHCID 57387427HCID 57387427—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 1 (Step 6) starting from N-{3-[5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-1H-benzimidazol-1-yl]phenyl}-N′-(2,2,2-trifluoroethyl)urea HCl salt and 2-tetrahydro-furancarboxylic acid, (Aldrich, Cat. No. 341517), LCMS (M+H)+: m/z=582.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754114B2
Source datasetuspto-grants-2014_06
ORD IDord-b434e496383c4d1a85871e57dca4c030
Source noteuspto-grants-2014_06