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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 407020Generated: October 30, 2026

(R)-Tetrahydro-3-furoic acid → HCID 57384356, compound

https://huagongshe.com/reaction/407020

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-Tetrahydro-3-furoic acidHCID 4661317—
ReactantN-{3-[7-(1-piperidin-4-yl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]phenyl}-N'-(2,2,2-trifluoroethyl)ureaHCID 67980436—
ProductHCID 57384356HCID 57384356—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 41 starting from N-{3-[7-(1-piperidin-4-yl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]phenyl}-N′-(2,2,2-trifluoroethyl)urea and tetrahydrofuran-3-carboxylic acid (Aldrich, Cat. No. 339954). LCMS (M+H)+: m/z=583.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754114B2
Source datasetuspto-grants-2014_06
ORD IDord-84264f8ede15431fbf2fba41d9b35bde
Source noteuspto-grants-2014_06