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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 407038Generated: October 30, 2026

3-Hydroxyazetidine hydrochloride → HCID 57385129, compound

https://huagongshe.com/reaction/407038

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxyazetidine hydrochlorideHCID 2759290—
Reactant2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)propanoic acidHCID 67980220—
ProductHCID 57385129HCID 57385129—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 54, Step 3 starting from 2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)propanoic acid and azetidin-3-ol hydrochloride (Oakwood and Cat. No. 013898). LCMS (M+H)+: m/z=529.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754114B2
Source datasetuspto-grants-2014_06
ORD IDord-a8f19e5dec004dd3a4a9bc5194acf29d
Source noteuspto-grants-2014_06