HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Difluoropyrrolidine hydrochloride → HCID 57385130, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Difluoropyrrolidine hydrochloride | HCID 24903482 | — |
| Reactant | 2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)propanoic acid | HCID 67980220 | — |
| Product | HCID 57385130 | HCID 57385130 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 54, Step 3 starting from 2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)propanoic acid and 3,3-difluoropyrrolidine hydrochloride (Matrix and Cat. No. 008716). LCMS (M+H)+: m/z=563.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754114B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-13d60a9a75dd4072877d950b60016873 |
| Source note | uspto-grants-2014_06 |