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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 407039Generated: October 28, 2026

3,3-Difluoropyrrolidine hydrochloride → HCID 57385130, compound

https://huagongshe.com/reaction/407039

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3-Difluoropyrrolidine hydrochlorideHCID 24903482—
Reactant2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)propanoic acidHCID 67980220—
ProductHCID 57385130HCID 57385130—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 54, Step 3 starting from 2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)propanoic acid and 3,3-difluoropyrrolidine hydrochloride (Matrix and Cat. No. 008716). LCMS (M+H)+: m/z=563.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754114B2
Source datasetuspto-grants-2014_06
ORD IDord-13d60a9a75dd4072877d950b60016873
Source noteuspto-grants-2014_06