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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 407059Generated: October 30, 2026

(R)-Tetrahydro-3-furoic acid → HCID 57386163, compound

https://huagongshe.com/reaction/407059

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-Tetrahydro-3-furoic acidHCID 4661317—
ReactantN-[3-(7-{1-[3-(cyanomethyl)azetidin-3-yl]-1H-pyrazol-4-yl]imidazo[1,2-b]pyridazin-3-yl)phenyl]-N'-(2,2,2-trifluoroethyl)ureaHCID 67980375—
ProductHCID 57386163HCID 57386163—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 77 starting from N-[3-(7-{1-[3-(cyanomethyl)azetidin-3-yl]-1H-pyrazol-4-yl}imidazo[1,2-b]pyridazin-3-yl)phenyl]-N′-(2,2,2-trifluoroethyl)urea and tetrahydrofuran-3-carboxylic acid. LCMS (M+H)+: m/z=594.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754114B2
Source datasetuspto-grants-2014_06
ORD IDord-4e55a1f7c8924d00b8f52d2c748a9635
Source noteuspto-grants-2014_06