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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 407063Generated: October 30, 2026

1-Pyrrolidinecarbonyl chloride → HCID 57386424, compound

https://huagongshe.com/reaction/407063

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Pyrrolidinecarbonyl chlorideHCID 70937—
ReactantN-[3-(7-{1-[3-(cyanomethyl)azetidin-3-yl]-1H-pyrazol-4-yl]imidazo[1,2-b]pyridazin-3-yl)phenyl]-N'-(2,2,2-trifluoroethyl)ureaHCID 67980375—
ProductHCID 57386424HCID 57386424—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 85 starting from N-[3-(7-{1-[3-(cyanomethyl)azetidin-3-yl]-1H-pyrazol-4-yl}imidazo[1,2-b]pyridazin-3-yl)phenyl]-N′-(2,2,2-trifluoroethyl)urea and 1-pyrrolidinecarbonyl chloride. LCMS (M+H)+: m/z=593.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754114B2
Source datasetuspto-grants-2014_06
ORD IDord-9ac8199fa1ad4242abf2e8681106d3b3
Source noteuspto-grants-2014_06