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HRID407118

反应详情

EQUATION

反应方程式

HRID 407118 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(S(=O)(=O)N[C@@H](c2ccccc2)[C@@H](N)c2ccccc2)cc1
HCID6612782

(1S,2S)-(+)-N-p-Tosyl-1,2-diphenylethylenediamine

C21H22N2O2S

结构：O=C1CCN(C(=O)OCc2ccccc2)c2ccccc21
HCID23726243

未命名化合物

PRODUCTS

生成物

1
结构：O=C(OCc1ccccc1)N1CC[C@H](O)c2ccccc21
HCID16117781

未命名化合物

收率 86.2%

PROCEDURE

实验过程

1-benzyloxycarbonyl-4-oxo-1,2,3,4-tetrahydroquinoline (281 mg), [RuCl2(benzene)]2 (25.0 mg) and (S,S)-TsDPEN (73.3 mg) were treated in the same manner as Example 4 to give 244 mg of (4S)-1-benzyloxycarbonyl-4-hydroxy-1,2,3,4-tetrahydroquinoline (optical purity: 97% ee, yield: 86%).