Stannous Chloride → HCID 68621262, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of N-methyl-6-(4-nitrophenyl)-1H-indazole-3-carboxamide (154 mg, 0.52 mmol) in ethanol (10 Ml), was added SnCl2 (588 mg, 2.6 mmol) and the mixture was stirred at 80° C. for 3 h. The mixture was cooled to rt and saturated sodium bicarbonate aqueous solution was added. The organic layer was extracted three times and the combined organaic layer was dried over sodium sulfate and concentrated under reduced pressure. The residue was triturated in ethyl acetate and hexane to give 6-(4-aminophenyl)-N-methyl-1H-indazole-3-carboxamide (130 mg).

Provenance & Evidence