反应详情

温度

90 °C

4-Azoniaspiro[3,4]octane chloride solution in water (88 ml) was added over 10 minutes to a solution of sodium hexaflurophosphate (50.3 g) in water (100 ml), followed by a line wash of water (12 ml). Further water (50 ml) was added to aid stirring of the thick suspension. The mixture was heated to 90° C. to aid stirring. The solid was filtered and washed with water (2×100 ml) and dried in a vacuum oven to give 4-azoniaspiro[3,4]octane hexafluorophosphate (54.14 g, 70.3% of theory).

1. washwash of water (12 ml)
2. additionFurther water (50 ml) was added to aid
3. stirringto aid stirring
4. filtrationThe solid was filtered
5. washwashed with water (2×100 ml)
6. customdried in a vacuum oven