HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 178434668, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Pyridinemethanamine | HCID 77317 | — |
| Reactant | HCID 178434665 | HCID 178434665 | — |
| Reactant | 2-(5-amino-3-methyl-1H-pyrazol-4-yl)-5-fluorobenzothiazole-6-sulfonyl chloride | HCID 178434667 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 178434668 | HCID 178434668 | 24% |
Reaction Steps
The title compound (15 mg) was prepared from crude 2-(5-amino-3-methyl-1H-pyrazol-4-yl)-5-fluorobenzothiazole-6-sulfonyl chloride, which had been derived from the chlorosulfonation of 90 mg of 4-(5-fluorobenzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine, 32 mg (0.30 mmol) of C-pyridin-4-ylmethylamine, and triethylamine (0.50 mL) in chloroform. MS (m/z, ES+): 419.1 (M+1, 100%), 210.0 (100%). Yield=24%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754233B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-f61300993bbf4f45b47a3d1fcd82e754 |
| Source note | uspto-grants-2014_06 |