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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 407556Generated: October 30, 2026

C35H42N4O6S → 18-[2-(4-Isopropylthiazole-2-yl)-7-methoxy-8-methylquinolin-4-yloxy]-2,15-dioxo-3,14-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxylic acid

https://huagongshe.com/reaction/407556

Reaction equation

Participants

RoleNameHCIDCharge
ReactantC35H42N4O6SHCID 66810935—
Reactant2-(4-Isopropylthiazol-2-YL)-7-methoxy-8-methylquinolin-4-OLHCID 178487692—
Product18-[2-(4-Isopropylthiazole-2-yl)-7-methoxy-8-methylquinolin-4-yloxy]-2,15-dioxo-3,14-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxylic acidHCID 66872141—

Reaction Steps

The title compound was prepared from intermediate 79 and quinoline 36 following the procedure (Steps D-F) reported for the preparation of 17-[2-(4-isopropylthiazole-2-yl)-7-methoxy-8-methylquinolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diazatricyclo-[13.3.0.04,6]octadec-7-ene-4-carboxylic acid (46): m/z=647 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754106B2
Source datasetuspto-grants-2014_06
ORD IDord-30454487915542768ed33496ae89e968
Source noteuspto-grants-2014_06