反应详情

Following the procedure in Example 148c, and starting with 149b (500 mg, 5.10 mmol, 1.0 eq.) and 3,5-dibromo-1-methylpyridin-2(1H)-one (2.04 g, 7.65 mmol, 1.5 eq.), 149c was obtained as a yellow solid (760 mg, 52%). MS-ESI: [M+H]+ 283.9.