Potassium Hydroxide → HCID 68227289, compound

Participants

Reaction Steps

The mixture of the crude 1,9-dichloro-10H-phenothiazine-10-carbaldehyde was dissolved in acetone (8 mL) and a solution of KOH (330 mg, 5.88 mmol) in EtOH (5.0 mL) was added. The mixture was stirred for 12 h at room temperature and then was evaporated to dryness to give a residue. The residue extracted with EtOAc and washed with 1M H3PO4. The organic layers were combined and dried over MgSO4, filtered and evaporated to give a residue. The residue was purified by flash silica gel chromatography to give 300 mg of a light yellow solid. LC/MS confirmed M+1=269.

Provenance & Evidence