Ammonium Acetate → HCID 178437991, compound

Participants

Reaction Steps

The title compound was prepared from 600 mg (2.508 mmol) (2E)-2-[(3-ethyl-1H-indazol-5-yl)-methylidene]-3-oxobutanenitrile (Example 7A), 256 mg (2.508 mmol) furan-2,4(3H,5H)-dione and 232 mg (3.010 mmol) ammonium acetate in analogy to the procedure described in Example 1 yielding 98 mg (12% of th.) of the racemic compound after purification by flash chromatography (silica gel; dichloromethane/methanol gradient, final mixture 30:1 v/v).

Provenance & Evidence