HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → Ethyl 3-[4-(benzyloxy)anilino]but-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | 4-Benzyloxyaniline | HCID 22860 | — |
| Product | Ethyl 3-[4-(benzyloxy)anilino]but-2-enoate | HCID 68726629 | 49.9% |
Reaction Steps
4-Benzyloxyaniline (10 g) and ethyl acetoacetate (6.9 g) were heated at 120° C. for 3 hours. The residue was purified by chromatography on silica eluting with a mixture of dichloromethane, and pentane. The desired fractions were concentrated and the sample evaporated to give the sub-title compound (7.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759348B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-9ab06209a42043369fc51d09ffedcba8 |
| Source note | uspto-grants-2014_06 |