HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68727240, compound → HCID 68725336, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68727240 | HCID 68727240 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68725336 | HCID 68725336 | — |
Reaction Steps
2-Methyl-6-nitro-4-(3-phenylpyrrolidin-1-yl)quinoline (0.29 g; see Preparation 7 above) and palladium on carbon (10%, 0.2 g) in ethanol (10 mL) and dichloromethane (4 mL) was stirred under a hydrogen atmosphere for 3 hours. The reaction mixture was filtered and concentrated to give the title compound as a thick yellow oil, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759348B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-f8326fbf00ba4e609921a44af54e8e5b |
| Source note | uspto-grants-2014_06 |