3-Fluorophenylboronic acid → HCID 58379323, compound

HRID 408794Notes

Reaction equation

HRID 408794 reaction equation
Br[C:2]1[N:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]2=[N:4][C:3]=1[C:11]([N:13]([O:15][CH3:16])[CH3:14])=[O:12].[F:17][C:18]1[CH:19]=[C:20](B(O)O)[CH:21]=[CH:22][CH:23]=1>>[F:17][C:18]1[CH:23]=[C:22]([C:2]2[N:6]3[CH:7]=[CH:8][CH:9]=[CH:10][C:5]3=[N:4][C:3]=2[C:11]([N:13]([O:15][CH3:16])[CH3:14])=[O:12])[CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 27339863-Fluorophenylboronic acidHCID 58379315HCID 58379315, compound

Product 1

HCID 58379323HCID 58379323, compoundYield 80%

Procedure

The desired compound was prepared according to the procedure of Example 1, step E, using 3-bromo-N-methoxy-N-methylimidazo[1,2-a]pyridine-2-carboxamide and (3-fluorophenyl)boronic acid as the starting materials in 80% yield. LCMS for C16H15FN3O2 (M+H)+: m/z=300.1.

Sources & evidence

ORD record
ord-f0b905b3ad874b1694c3297b86b136d6
Source dataset
uspto-grants-2014_06
Patent number
US08759359B2

Reaction notes

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