Cyclopropanemethanamine → Ethyl 4-(3-(cyclopropylmethyl)ureido)benzoate

Participants

Reaction Steps

To cyclopropylmethanamine (57.5 mmol, 4.99 ml, 4.09 g) in dichloromethane (40 mL) was added to ethyl 4-isocyanatobenzoate (52.3 mmol, 10 g) in dichloromethane (45 mL) and the reaction stirred overnight. The reaction was then concentrated under reduced pressure to give the title compound (14.7 g).

Provenance & Evidence