Acetonitrile → HCID 58055793, compound

Participants

Reaction Steps

Methyl 6-((methylsulfonyloxy)methyl)picolinate (300 mg, 1.22 mmol), 1-(cyclo-butylmethyl)-3-(2-fluoro-4-(piperazine-1-carbonyl)phenyl)urea (391 mg, 1.22 mmol) and potassium carbonate (505 mg, 3.66 mmol) were combined and stirred in acetonitrile for 18 hours. The reaction mixture was concentrated at reduced pressure. The resulting residue was taken up in dichloromethane, washed with water, dried over sodium sulfate and concentrated under vacuum to afford the title compound (407 mg).

Provenance & Evidence