Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → HCID 86662562, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | p-Toluenesulfonate | HCID 85570 | — |
| 반응물 | 1-Dichlorophosphoryloxynaphthalene | HCID 575631 | — |
| 반응물 | benzyloxy-L-alanine | HCID 13028072 | — |
| 생성물 | HCID 86662562 | HCID 86662562 | 89% |
반응 단계
Using the general procedure for synthesizing naphthyl (aminoacid ester) phosphorochloridates the tosylate salt of benzyloxy-L-alanine (1.5 g), naphthalen-1-yl phosphorodichloridate (1.10 g), TEA (1.14 mL), and DCM (20 mL) were combined to give (2S)-benzyl 2-(chloro(naphthalen-1-yloxy)-phosphorylamino)-propanoate in an 89% yield (1.53 g), as a pale yellow thick oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08759318B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-df86005e653c4a39b160ebaba0a455e7 |
| 출처 메모 | uspto-grants-2014_06 |