Glycine → HCID 67110507, compound

HRID 409218Notes

Reaction equation

HRID 409218 reaction equation
[CH3:1][C:2]1[CH:20]=[CH:19][CH:18]=[C:17]([CH3:21])[C:3]=1[O:4][C:5]1[CH:6]=[C:7]([C:14]([OH:16])=O)[C:8](=[CH:12][CH:13]=1)[C:9]([OH:11])=O.[NH2:22][CH2:23][C:24]([OH:26])=[O:25]>O>[CH3:21][C:17]1[CH:18]=[CH:19][CH:20]=[C:2]([CH3:1])[C:3]=1[O:4][C:5]1[CH:6]=[C:7]2[C:8](=[CH:12][CH:13]=1)[C:9](=[O:11])[N:22]([CH2:23][C:24]([OH:26])=[O:25])[C:14]2=[O:16]

Participants

4

Reactant 2

HCID 750GlycineHCID 17846255HCID 17846255, compound

Product 1

HCID 67110507HCID 67110507, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4-(2,6-Dimethyl-phenoxy)-phthalic acid and an equimolar amount of glycine were ground thoroughly together in a mortar. The mixture was then heated at 220 to 240° C. in an oil-bath in vacuo until the formation of water ceased (ca. 30 min) to give the title compound as a dark glass (yield: 99%); MS-(−)-ion: M−1=324.5.

Workup

  1. custom(ca. 30 min)

Sources & evidence

ORD record
ord-4478babcc3ae4a8a83b3fb87ebf0d5c0
Source dataset
uspto-grants-2014_06
Patent number
US08759373B2

Reaction notes

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