HCID 86617068, compound → HCID 67110515, compound

HRID 409228Notes

Reaction equation

HRID 409228 reaction equation
[CH3:1][O:2][C:3]([C:5]1[N:6]=[C:7](Br)[C:8]2[C:13]([C:14]=1[OH:15])=[C:12]([O:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH:11]=[CH:10][CH:9]=2)=[O:4].[C:24]([Cu])#[N:25]>>[CH3:1][O:2][C:3]([C:5]1[N:6]=[C:7]([C:24]#[N:25])[C:8]2[C:13]([C:14]=1[OH:15])=[C:12]([O:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH:11]=[CH:10][CH:9]=2)=[O:4]

Participants

3

Reactant 2

HCID 86617068HCID 86617068, compoundHCID 178418546HCID 178418546, compound

Product 1

HCID 67110515HCID 67110515, compound

Procedure

The title compound was synthesized from 1-Bromo-4-hydroxy-5-phenoxy-isoquinoline-3-carboxylic acid methyl ester and CuCN in analogy to example 3a; MS-(+)-ion: M+1=320.8.

Sources & evidence

ORD record
ord-75502a505cb44f239eaa4d1da64514bd
Source dataset
uspto-grants-2014_06
Patent number
US08759373B2

Reaction notes

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