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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 409240Generated: October 29, 2026

N-bromobutanimide → 1-Bromo-4-hydroxy-8-(2-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl ester

https://huagongshe.com/reaction/409240

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-bromobutanimideHCID 67184—
ReactantHCID 67110132HCID 67110132—
Product1-Bromo-4-hydroxy-8-(2-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl esterHCID 86617070—

Reaction Steps

The title compound was synthesized from 4-hydroxy-8-(2-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl ester and N-bromosuccinimide in analogy to example 19e; MS-(+)-ion: M+1, 79Br/81Br=404.3 and 406.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759373B2
Source datasetuspto-grants-2014_06
ORD IDord-b6b074dde66b470488146b252e259795
Source noteuspto-grants-2014_06