HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Benzyl-1-bromo-4-hydroxy-isoquinoline-3-carboxylic acid methyl ester → 7-Benzyl-1-cyano-4-hydroxy-isoquinoline-3-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Benzyl-1-bromo-4-hydroxy-isoquinoline-3-carboxylic acid methyl ester | HCID 86617071 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Product | 7-Benzyl-1-cyano-4-hydroxy-isoquinoline-3-carboxylic acid methyl ester | HCID 67110377 | — |
Reaction Steps
The title compound was synthesized from 7-benzyl-1-bromo-4-hydroxy-isoquinoline-3-carboxylic acid methyl ester and CuCN in analogy to example 3a; MS-(−)-ion: M−1=317.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759373B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-c97270ccafc54dd8818aad6a623f1add |
| Source note | uspto-grants-2014_06 |