Acetic Acid → HCID 67330851, compound

Participants

Reaction Steps

A 5 mL vial was charged with a magnetic stirbar, the aromatic aldehyde (0.1 mmol), dimethylformamide (1.5 mL) and triethylamine (0.3 mmol). The mixture was allowed to stir for 10 min at room temperature. Acetic acid (0.75 mmol) and sodium borohydride (0.15 mmol) were then added and allowed to stir for 5 min prior to addition of Compound 13 (0.1 mmol). The product was purified by mass-directed column chromatography. LC-MS, M+1=368.3

Provenance & Evidence