HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 17925871, compound → 4-CarboxyMethyl-cyclohexanecarboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 17925871 | HCID 17925871 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-CarboxyMethyl-cyclohexanecarboxylic acid ethyl ester | HCID 15896192 | 42% |
Reaction Steps
To a solution of 2-(4-(ethoxycarbonyl)cyclohexylidene)acetic acid (6.0 g, 28.3 mmol) in EtOH (50 ml) was slowly added 10% Pd/C (306 mg). The solution was hydrogenated overnight. The catalyst was filtered off. The filtrate was concentrated in vacuo to afford 2.5 g of product as colorless oil (42%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759548B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-884459c38d28486abf5c93ec89e88205 |
| Source note | uspto-grants-2014_06 |