Benzeneacetic acid, 4-bromo- → 2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone

HRID 410032Notes

Reaction equation

HRID 410032 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:22])[CH2:10][CH:11]1[CH2:16][CH2:15][CH:14](C(OCC)=O)[CH2:13][CH2:12]1.[Br:23]C1C=CC(CC(O)=O)=CC=1>>[Br:23][C:14]1[CH:15]=[CH:16][C:11]([CH2:10][C:9]([C:3]2[CH:4]=[CH:5][C:6]([OH:8])=[CH:7][C:2]=2[OH:1])=[O:22])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 74654Benzeneacetic acid, 4-bromo-HCID 67367789HCID 67367789, compound

Product 1

HCID 20634662-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanoneYield 27.9%

Procedure

Followed Step 4 of Intermediate C, starting with 2-(4-bromophenyl)acetic acid to give product as an orange powder (20 g, 27.9%). MS (ESI): m/z 307.0, 309.0 [M+1]+, [M+3]+.

Sources & evidence

ORD record
ord-bd712b8baf544756a1b728aa6543cbbb
Source dataset
uspto-grants-2014_06
Patent number
US08759548B2

Reaction notes

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