1,1'-Thiocarbonyldi-2(1H)-pyridone → N-(2,4-Dimethyl-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide

HRID 410083Notes

Reaction equation

HRID 410083 reaction equation
[NH2:1][C:2]1[C:3]([CH3:17])=[C:4]([CH:13]=[CH:14][C:15]=1[CH3:16])[CH2:5][NH:6][C:7](=[O:12])[C:8]([CH3:11])([CH3:10])[CH3:9].[C:18](N1C=CC=CC1=O)(N1C=CC=CC1=O)=[S:19]>>[CH3:17][C:3]1[C:2]([N:1]=[C:18]=[S:19])=[C:15]([CH3:16])[CH:14]=[CH:13][C:4]=1[CH2:5][NH:6][C:7](=[O:12])[C:8]([CH3:11])([CH3:10])[CH3:9]

Participants

3

Reactant 2

HCID 8531621,1'-Thiocarbonyldi-2(1H)-pyridoneHCID 56839979N-(3-Amino-2,4-dimethyl-benzyl)-2,2-dimethyl-propionamide

Product 1

HCID 56840195N-(2,4-Dimethyl-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamideYield 65%

Procedure

The title compound is prepared from N-(3-amino-2,4-dimethyl-benzyl)-2,2-dimethyl-propionamide, 1,1′-thiocarbonyldi-2-pyridone in analogy to step Af.

Sources & evidence

ORD record
ord-a2e6f5d35eeb4067ae2ce72ebac08800
Source dataset
uspto-grants-2014_06
Patent number
US08759537B2

Reaction notes

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