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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 410107Generated: October 29, 2026

4-Amino-2-fluoro-5-nitrobenzoic acid → HCID 178507810, compound

https://huagongshe.com/reaction/410107

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2-fluoro-5-nitrobenzoic acidHCID 59785337—
ReactantHCID 178507811HCID 178507811—
ReactantHCID 178511531HCID 178511531—
CatalystPalladiumHCID 23938—
ProductHCID 178507810HCID 178507810—

Reaction Steps

The subtitle compound is prepared from N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-fluoro-4-amino-5-nitro-benzoic acid amide (prepared from 2-fluoro-4-amino-5-nitro-benzoic acid, trans-4-trifluoromethyl-cyclohexylamine in analogy to the example 2d) with Pd/C and H2 in analogy to example 1f.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759537B2
Source datasetuspto-grants-2014_06
ORD IDord-2d917c0f074240128f86962b8b9c77fb
Source noteuspto-grants-2014_06