HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-{2,6-Dichloro-3-[(2,2-dimethyl-propionylamino)-methyl]phenylamino}-6-(2,2,2-trifluoroethoxy)-7-fluoro-1H-benzimidazole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178496991 | HCID 178496991 | — |
| Product | 2-{2,6-Dichloro-3-[(2,2-dimethyl-propionylamino)-methyl]phenylamino}-6-(2,2,2-trifluoroethoxy)-7-fluoro-1H-benzimidazole-5-carboxylic acid | HCID 178447327 | — |
Reaction Steps
The subtitle compound is prepared from 2-{2,6-dichloro-3-[(2,2-dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2,2-trifluoroethoxy)-7-fluoro-1H-benzimidazole-5-carboxylic acid methyl ester and NaOH in analogy to example 28a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759537B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-5817f2d056a1418a8a2aff385fd939a3 |
| Source note | uspto-grants-2014_06 |