Hydrochloric Acid → HCID 178481216, compound

Participants

Reaction Steps

A mixture of N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-{2,6-dichloro-3-[(tert-butoxy-carbonylamino)-methyl]-phenylamino}-6-(2,2-difluoroethoxy)-1-methyl-1H-benzimidazole-5-carboxylic acid amide (350 mg, 0.504 mmol), 6 M aq. HCl-solution (15 mL) and THF (15 mL) is stirred overnight, the mixture is concentrated and directly used in the next step.

Provenance & Evidence