HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Acetylpiperazine → (3aSR,10RS)-2-[2-(4-Acetyl-piperazin-1-yl)-ethyl]-10-(3-hydroxy-phenyl)-6-methoxy-3a-methyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Acetylpiperazine | HCID 83795 | — |
| Reactant | (+)-2-(2-Bromo-ethyl)-10-(3-hydroxy-phenyl)-6-methoxy-3a-methyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione | HCID 68939448 | — |
| Product | (3aSR,10RS)-2-[2-(4-Acetyl-piperazin-1-yl)-ethyl]-10-(3-hydroxy-phenyl)-6-methoxy-3a-methyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione | HCID 68940052 | — |
Reaction Steps
The title compound is prepared similarly as described for example 29 using (3aSR,10RS)-2-(2-Bromoethyl)-10-(3-hydroxy-phenyl)-6-methoxy-3a-methyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]-fluorene-1,3-dione (example 24) and N-acetyl piperazine as starting materials. MS: m/z (MH+)=532.1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08530493B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-38105208dc174948be05afc2d2b82921 |
| Source note | uspto-grants-2013_09 |