HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → ((1,1-Dimethyl-2-propynyl)oxy)trimethylsilane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | 2-Methyl-3-butyn-2-ol | HCID 8258 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | ((1,1-Dimethyl-2-propynyl)oxy)trimethylsilane | HCID 87344 | 57.5% |
Reaction Steps
To a solution of 2-methylbut-3-yn-2-ol (140 g, 1.67 mol) was added DMAP (20 g 0.17 mol), Et3N (927 ml, 3.33 mol) and TMS-Cl (289 g, 2.66 mol) at 5 degree under a nitrogen atmosphere. After being stirred one hour, the mixture was washed with water, dried (MgSO4), filtered, concentrated, and distilled to obtain trimethyl[(2-methylbut-3-yn-2-yl)oxy]silane (150 g, 0.96 mol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759366B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-b49f4e4b7bc34026b242b9757d4ecda6 |
| Source note | uspto-grants-2014_06 |