HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propane, 1-chloro-3-isocyanato- → (3aSR,10RS)-6-Chloro-2-(3-chloro-propyl)-10-(3-hydroxy-phenyl)-3a-methyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propane, 1-chloro-3-isocyanato- | HCID 166752 | — |
| Reactant | (1RS,3SR)-6-Chloro-1-(3-hydroxy-phenyl)-3-methyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid methyl ester | HCID 68887684 | — |
| Product | (3aSR,10RS)-6-Chloro-2-(3-chloro-propyl)-10-(3-hydroxy-phenyl)-3a-methyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione | HCID 68946299 | — |
Reaction Steps
The title compound is prepared analogously to the procedure described for example 22, using chloro propyl isocyanate and (1RS,3SR)-6-chloro-1-(3-hydroxy-phenyl)-3-methyl-2,3,4,9-tetrahydro-1H-betacarboline-3-carboxylic acid methyl ester. MS: m/z (MH+)=457.9
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08530493B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-385056fbcff044ad9c4b674e894bf209 |
| Source note | uspto-grants-2013_09 |