Propane, 1-chloro-3-isocyanato- → HCID 68938455, compound

HRID 41049Notes

Reaction equation

HRID 41049 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][N:5]=[C:6]=[O:7].C[O:9][C:10]([C:12]1([CH3:33])[CH2:24][C:23]2[C:22]3[C:17](=[CH:18][CH:19]=[C:20]([Br:25])[CH:21]=3)[NH:16][C:15]=2[CH:14]([C:26]2[CH:31]=[CH:30][CH:29]=[C:28]([OH:32])[CH:27]=2)[NH:13]1)=O>>[Br:25][C:20]1[CH:21]=[C:22]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15]1[CH:14]([C:26]3[CH:31]=[CH:30][CH:29]=[C:28]([OH:32])[CH:27]=3)[N:13]3[C:6](=[O:7])[N:5]([CH2:4][CH2:3][CH2:2][Cl:1])[C:10](=[O:9])[C:12]3([CH3:33])[CH2:24][C:23]2=1

Participants

3

Reactant 2

HCID 166752Propane, 1-chloro-3-isocyanato-HCID 68850651(1RS,3SR)-6-bromo-1-(3-hydroxy-phenyl)-3-methyl-2,3,4,9-tetrahydro-1H-betacarboline-3-carboxylic acid methyl ester

Product 1

HCID 68938455HCID 68938455, compound

Procedure

The title compound is prepared analogously to the procedure described for example 22, using chloro propyl isocyanate and (1RS,3SR)-6-bromo-1-(3-hydroxy-phenyl)-3-methyl-2,3,4,9-tetrahydro-1H-betacarboline-3-carboxylic acid methyl ester. MS: m/z (MH+)=501.9/503.9

Sources & evidence

ORD record
ord-1a90a99e5d214287a2111babfe036757
Source dataset
uspto-grants-2013_09
Patent number
US08530493B2

Reaction notes

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