HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → Methyl 4-(methylamino)-3-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Methyl 4-chloro-3-nitrobenzoate | HCID 735797 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 4-(methylamino)-3-nitrobenzoate | HCID 7650848 | — |
Reaction Steps
4-Methylamino-3-nitro-benzoic acid methyl ester (822 mg) was prepared by following General Procedure A starting from methyl 4-chloro-3-nitrobenzoate (1.0 g) and methylamine (2 M in THF, 6.95 mL) in DMF. The crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-7f3c860dc8984f65a22b71e866d028cd |
| Source note | uspto-grants-2014_06 |