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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 41085Generated: October 27, 2026

5-Chloro-N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide → 5-Chloro-n-{[(5s)-3-(3-fluoro-4-morpholinophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}-2-thiophenecarboxamide n-oxide

https://huagongshe.com/reaction/41085

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamideHCID 10138114—
Reactant3-Hydroperoxyphthalic acidHCID 19809706—
Product5-Chloro-n-{[(5s)-3-(3-fluoro-4-morpholinophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}-2-thiophenecarboxamide n-oxideHCID 87064343—

Reaction Steps

is obtained by treating 5-chloro-N-{[(5S)-3-(3-fluoro-4-morpholinophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}-2-thiophenecarboxamide from Example 1 with the magnesium salt of monoperoxyphthalic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08530505B2
Source datasetuspto-grants-2013_09
ORD IDord-31196581dda34d6b8a93b2ec33194a33
Source noteuspto-grants-2013_09