HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → Methyl 4-[(2-methylpropyl)amino]-3-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | Methyl 4-chloro-3-nitrobenzoate | HCID 735797 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 4-[(2-methylpropyl)amino]-3-nitrobenzoate | HCID 67334709 | 81.2% |
Reaction Steps
4-Isobutylamino-3-nitro-benzoic acid methyl ester (950.0 mg) was prepared by following General Procedure A starting from methyl 4-chloro-3-nitrobenzoate (1.0 g) and isobutyl amine (402.0 mg) in DMF (10.0 mL). The crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-78d043cda1874fedb620d3037bde705b |
| Source note | uspto-grants-2014_06 |