64910-48-1 → 4-Amino-3-(methylamino)benzonitrile

HRID 410949Notes

Reaction equation

HRID 410949 reaction equation
[CH3:1][NH:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][C:10]=1[N+:11]([O-])=O)[C:6]#[N:7]>[Pd]>[NH2:11][C:10]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[NH:2][CH3:1]

Participants

3

Reactant 1

HCID 1101939864910-48-1

Product 1

HCID 110080674-Amino-3-(methylamino)benzonitrileYield 0.1%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

4-Amino-3-methylamino-benzonitrile (1.17 mg) was prepared by following General Procedure B starting from 3-methylamino-4-nitro-benzonitrile (1.33 g) and Pd/C (10% by weight, 133 mg). The crude product was used in the next step without further purification.

Workup

  1. customThe crude product was used in the next step without further purification

Sources & evidence

ORD record
ord-d79cc169abc14c7ba5ba7ed911ad189e
Source dataset
uspto-grants-2014_06
Patent number
US08759535B2

Reaction notes

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