Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(2-Chloroethyl)dibenzylamine → Dibenzyl-[2-(3-fluoro-propoxy)-ethyl]-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(2-Chloroethyl)dibenzylamine | HCID 5820 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 3-Fluoro-1-propanol | HCID 68042 | — |
| 촉매 | Tetrabutylammonium Bromide | HCID 74236 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | Dibenzyl-[2-(3-fluoro-propoxy)-ethyl]-amine | HCID 67333072 | 67.6% |
반응 단계
Dibenzyl-[2-(3-fluoro-propoxy)-ethyl]-amine (770 mg) was prepared by following General Procedure S starting from dibenzyl-(2-chloro-ethyl)-amine (1 g), 3-fluoro-propan-1-ol (295 mg), 50% (w/w) KOH solution (4.25 mL) and tetrabutylammonium bromide (130 mg) in dioxane (4.25 mL).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08759535B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-26aef49b7bcf4e2a82310e6cf581f947 |
| 출처 메모 | uspto-grants-2014_06 |