HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Dibenzyl-[3-(2-benzyloxy-ethoxy)-propyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(Benzyloxy)ethyl 4-methylbenzenesulfonate | HCID 561375 | — |
| Reactant | 3-(Dibenzylamino)-1-propanol | HCID 4437007 | — |
| Catalyst | Tetrabutylammonium hydrogen sulfate | HCID 94433 | — |
| Product | Dibenzyl-[3-(2-benzyloxy-ethoxy)-propyl]-amine | HCID 67332452 | 29.7% |
Reaction Steps
Dibenzyl-[3-(2-benzyloxy-ethoxy)-propyl]-amine (378 mg) was prepared by following General Procedure W starting from toluene-4-sulfonic acid 2-benzyloxy-ethyl ester (1.0 g), 3-dibenzylamino-propan-1-ol (1.08 g), 50% aqueous sodium hydroxide solution (1.3 g in 1.3 mL of water), and tetrabutylammonium hydrogen sulfate (111 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-855ab1d47c4d4a2a97e8c4ac842ee0c1 |
| Source note | uspto-grants-2014_06 |